Uncovering the principle by which DNA replication initiation sites are determined in the human genome

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication ...
Science Daily

When it comes to DNA replication, humans and baker's yeast are more alike than different

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for the ...

Newly Discovered DNA “Danger Zone” Could Change What We Know About Human Disease

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...

New mutation hotspot discovered in human genome

Researchers have discovered new regions of the human genome particularly vulnerable to mutations. These altered stretches of ...

Backup DNA repair system could be cancer's weak spot

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...
Inverse

Ancient Viruses Left Their DNA In Humans — And They Could Help Trigger These Common Diseases

Around 8 percent of human DNA is made up of genetic sequences acquired from ancient viruses. These sequences, known as human endogenous retroviruses (or Hervs), date back hundreds of thousands to ...
CNN

Oldest human DNA reveals lost branch of the human family tree

Sign up for CNN’s Wonder Theory science newsletter. Explore the universe with news on fascinating discoveries, scientific advancements and more. Scientists say they ...
EurekAlert!

When it comes to DNA replication, humans and baker’s yeast are more alike than different

DNA replication is a complex process with many moving parts. In baker's yeast, the molecular complex Ctf18-RFC keeps parts of the replication machinery from falling off the DNA strand. Human cells use ...